Progest-E Complex contains approximately 3 mg of progesterone per small drop.
Individual progesterone needs and appropriate patterns of use can vary based on age, menstrual status, hormone levels and other health considerations.
The manufacturer provides different usage information for women who are menstruating, perimenopausal or postmenopausal. See the “How Progest-E Is Commonly Used” section below for additional information.
Consult your healthcare provider to determine whether progesterone is appropriate for you and how it should be used for your individual needs.
Storage: Refrigerate after opening.
Best ways to use Progest-E Complex Replenishing Oil:
For PMS:
The normal pattern of progesterone secretion during the month is for the ovaries to produce a large amount in the 2nd two weeks of the menstrual cycle, ( i.e. day 14 through day 28) beginning at ovulation and ending around the beginning of menstruation, and then to produce little for the following two weeks. An average person produces about 30 milligrams daily during the 2nd two weeks. Progest E complex contains approximately 3 milligrams of progesterone per small drop. Three to four drops, or about 9 -12 milligrams of progesterone, is often enough to bring the progesterone level up to normal. That amount can be taken day 14 through 28 of the menstrual cycle. This amount may be repeated once or twice during the day as needed to alleviate symptoms. Since an essential mechanism of progesterone’s action involves its opposition to estrogen, smaller amounts are effective when estrogen production is low, and if estrogen is extremely high, even large supplements of progesterone will have no clear effect; in that case, it is essential to regulate estrogen metabolism, by improving the diet, correcting a thyroid deficiency, etc. ( Unsaturated fat is antithyroid and synergizes with estrogen.)
Perimenopausal:
The symptoms and body changes leading up to menopause are associated with decreasing production of progesterone, at a time when estrogen may be at a lifetime high. The cyclic use of progesterone, two weeks on, two weeks off, will often keep the normal menstrual cycle going. Three to four drops, providing ten or twelve milligrams of progesterone, is typical for a day, but some women prefer to repeat that amount. Progesterone is always more effective when the diet contains adequate protein, and where there isn’t an excessive amount of unsaturated fat in the diet.
Postmenopausal:
Some women continue the cyclic use of progesterone after menopause, because the pituitary gland and brain may continue to cycle long after menstruation has stopped, and progesterone is an important regulator of pituitary and brain function. The cycling pituitary affects the adrenal glands and other organs, and progesterone tends to protect against the unopposed actions of prolactin, cortisol, and adrenal androgenic hormones. Progesterone’s effects on the pituitary apparently contribute to its protective effect against osteoporosis, hypertension, hirsutism, etc. But some women prefer to use progesterone without interruption after the menopause, for its protective anti-stress effects. Slender people usually find that two or three drops are enough, but this amount may be repeated once or twice as needed to relieve symptoms. Adequate protein in the diet and good thyroid function help the body to produce its own progesterone; even if the ovaries have been removed, the adrenal glands and brain continue to produce progesterone.
California Proposition 65 WARNING: This product contains progesterone, a chemical known to the State of California to cause cancer. Consult with your physician before using this product.
Storage Instructions
Refrigeration or Cool, Dark Storage
For optimal freshness, store Progest-E in the refrigerator or in a cool, dark location away from direct sunlight and excessive heat.
Natural vitamin E can deteriorate with prolonged exposure to light and high temperatures. Proper storage helps preserve the quality of the oil-based formula.
Refrigeration is recommended for long-term storage or during particularly warm weather, but it is not required under normal cool storage conditions.
How to Use Progest-E After Refrigeration
Because the formula becomes more viscous when cold:
- Remove the bottle from the refrigerator approximately 20–30 minutes before use.
- Keep the cap securely closed while the oil gradually warms toward room temperature.
- Once the oil flows more easily, dispense the intended amount.
- Close the bottle and return it to its storage location.
Do not microwave the bottle or expose it to direct heat to thin the oil.
Storing the Bottle Upside Down
When the bottle is nearly empty, Kenogen recommends storing it upside down, with the cap securely closed, in a small glass inside the refrigerator.
This keeps the remaining oil near the dispensing tip and makes it easier to access.
Important: Keep a full or nearly full bottle upright. Inverting a full bottle may cause the oil to dispense too quickly when opened.
Additional Storage Precautions
- Protect from direct sunlight and prolonged heat exposure.
- Keep the cap tightly closed.
- Avoid contaminating the dispensing tip.
- Do not freeze.
- Keep out of reach of children.
- Follow any expiration date or additional storage instructions printed on the bottle.
Important Safety Information
Progest-E contains progesterone, a biologically active hormone. Consult a qualified healthcare professional before use, particularly if pregnant, breastfeeding, taking hormonal medications, or managing a hormone-sensitive medical condition.
Do not use progesterone to self-treat unexplained vaginal bleeding or other undiagnosed symptoms. Individual medical guidance is important for determining appropriate use.
